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Certified Clinical Exercise Physiologist

Sponsoring Organization: American College of Sports Medicine

Date Obtained: 2009-01-01

Expertise

Research Interests

Her research interests include examining how short term alterations in physical activity (or inactivity) impact cardiometabolic health in healthy individuals, individuals with chronic diseases (type 2 diabetes, cardiovascular disease), as well as during pregnancy.

Articles

Mohammadi, A., Reynolds, L. and McCann, R. (2025). Ankle cartilage health and physical activity in adults with a history of lateral ankle sprain. Physiotherapy Theory and Practice , pp. 1-12.

Reynolds, L., Williams, T., Harden, J., Twiddy, H. and Kearney, M. (2022). The Impact of Removal of Exercise for 3 Days on Glycemic Control in Older Active Adults. The FASEB Journal 36 (S1).

Hao, Z., Wang, D. and Reynolds, L. (2020). Post-exercise Response of Arterial Parameters for Arterial Health Assessment Using a Microfluidic Tactile Sensor and Vibration-Model-Based Analysis: A Proof-of-Concept Study. Cardiovascular Engineering and Technology 11 (3) , pp. 295-307.

Wang, D., Reynolds, L., Alberts, T., Vahala, L. and Hao, Z. (2019). Model-based analysis of arterial pulse signals for tracking changes in arterial wall parameters: a pilot study. Biomechanics and Modeling in Mechanobiology 18 (6) , pp. 1629-1638.

Preston, J. D., Reynolds, L. and Pearson, K. L. (2018). Developmental origins of health span and life span: A mini-review. Gerontology 64 (3) , pp. 237-245.

Credeur, D. P.., Reynolds, L., Holwerda, S. W.., Vranish, J. R.., Young, B. E.., Wang, J., Thyfault, J. P.. and Fadel, P. J.. (2018). Influence of physical inactivity on arterial compliance during a glucose challenge. Experimental Physiology , pp. n/a--n/a.

Reynolds, L., Pollack, R., Charnigo, R., Rashid, C., Stromberg, A., O'Brien, J. and Pearson, K. (2017). Increased birth weight is associated with altered gene expression in neonatal foreskin. Journal of Developmental Origins of Health and Disease.

Reynolds, L., Credeur, D. P., Manrique, C., Padilla, J., Fadel, P. J. and Thyfault, J. P. (2017). Obesity, type 2 diabetes, and impaired insulin-stimulated blood flow: role of skeletal muscle NO synthase and endothelin-1. Journal of Applied Physiology 122 (1) , pp. 38–47.

Reynolds, L., Dickens, B. J., Green, B. B., Marsit, C. J. and Pearson, K. J. (2017). Using neonatal skin to study the developmental programming of aging. Experimental gerontology 94 , pp. 93–98.

Reynolds, L., Credeur, D. P., Holwerda, S. W., Leidy, H. J., Fadel, P. J. and Thyfault, J. P. (2015). Acute inactivity impairs glycemic control but not blood flow to glucose ingestion. Medicine and science in sports and exercise 47 (5) , pp. 1087.

Holwerda, S. W., Reynolds, L., Restaino, R. M., Credeur, D. P., Leidy, H. J., Thyfault, J. P. and Fadel, P. J. (2015). The influence of reduced insulin sensitivity via short-term reductions in physical activity on cardiac baroreflex sensitivity during acute hyperglycemia. Journal of Applied Physiology 119 (12) , pp. 1383–1392.

Bauer, L., Reynolds, L., Douglas, S., Kearney, M., Hoertel, H., Shafer, R., Thyfault, J. and Leidy, H. (2015). A pilot study examining the effects of consuming a high-protein vs normal-protein breakfast on free-living glycemic control in overweight/obese ‘breakfast skipping’ adolescents. International journal of obesity 39 (9) , pp. 1421-4.

Abraham, K. A., Kearney, M. L., Reynolds, L. and Thyfault, J. P. (2015). Red wine enhances glucose-dependent insulinotropic peptide (GIP) and insulin responses in type 2 diabetes during an oral glucose tolerance test. Diabetology international 7 (2) , pp. 173–180.

Jiang, J., Boyle, L., Mikus, C., Oberlin, D., Fletcher, J., Thyfault, J. and Hinton, P. (2014). The effects of improved metabolic risk factors on bone turnover markers after 12 weeks of simvastatin treatment with or without exercise. Metabolism 63 (11) , pp. 1398-408.

Credeur, D., Holdwera, S., Boyle, L., Vianna, L., Kim, A. and Fadel, P. (2014). Effect of Aging on Carotid Baroreflex Control of Blood Pressure and Leg Vascular Conductance in Women. American Journal of Physiology - Heart and Circulatory Physiology.

Reynolds, L., Credeur, D., Jenkins, N., Padilla, J., Leidy, H., Thyfault, J. and Fadel, P. (2013). Impact of Reduced Daily Physical Activity on Conduit Artery Flow-Mediated Dilation and Circulating Endothelial Microparticles. Journal of Applied Physiology.

Mikus, C., Boyle, L., Borengasser, S., Oberlin, D., Naples, S., Fletcher, J., Meers, G., Ruebel, M., Laughlin, M., Dellsperger, K., Fadel, P. and Thyfault, J. (2013). Simvastatin impairs exercise training adaptations. Journal of the American College of Cardiology 62 (8) , pp. 709-14.

Jenkins, N., Padilla, J., Boyle, L., Credeur, D., Laughlin, M. and Fadel, P. (2013). Disturbed Blood Flow Induces Activation and Apoptosis of the Human Vascular Endothelium. Hypertension 61 (3) , pp. 615-21.

Mikus, C., Oberlin, D., Libla, D., Boyle, L. and Thyfault, J. (2012). Glycaemic control is improved by 7 days of aerobic exercise training in patients with type 2 diabetes. Diabetologia 55 (5) , pp. 1417-23.

Mikus, C., Fairfax, S., Libla, J., Boyle, L., Vianna, L., Oberlin, D., Uptergrove, G., Deo, S., Kim, A., Kanaley, J., Fadel, P. and Thyfault, J. (2011). Seven days of aerobic exercise training improves conduit artery blood flow following glucose ingestion in patients with type 2 diabetes. Journal of Applied Physiology 111 (3) , pp. 657-64.

Reynolds, L. and Nagelkirk, P. (2010). The Effects of Whole Body Vibration and Exercise on Fibrinolysis in Men. European Journal of Applied Physiology 110 (5).

Conference Proceeding

Rahman, M. Mahfuzur., Twiddy, H., Reynolds, L. and Hao, Z. (2021). Measurement of Post-Exercise Response of Local Arterial Parameters Using an Adjustable Microfluidic Tactile Sensor 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (pp. 1284-1287) IEEE.

Chavan, N. R., Pollack, R. E., Reynolds, L., Dickens, B., O’Brien, J. M. and Pearson, K. J. (2017). Maternal Pre-Pregnancy Body Mass Index (BMI) Predicts Gene Expression in a Novel Human Model REPR��������CTIVE SCIENCES (pp. 128A–128A).

Chavan, N. R., Reynolds, L., Jarrell, A. L., Dickens, B., O’Brien, J. M. and Pearson, K. J. (2016). Human Foreskin as a Model to Study Insulin Signaling and Adipogenesis in Neonates. REPR��������CTIVE SCIENCES (pp. 234A–234A).

Chavan, N. R., Jarrell, A. L., Pollack, R. I., Reynolds, L., O’Brien, J. M. and Pearson, K. J. (2016). Parity Influences Neonatal Gene Expression. REPR��������CTIVE SCIENCES (pp. 313A–313A).

Reynolds, L., Rashid, C. S., Platt, K. M., Jarrell, A. L., Swanson, H. I. and Pearson, K. J. (2015). Maternal Polychlorinated Biphenyl 126 Exposure Alters Hepatic Gene Expression in Offspring. REPR��������CTIVE SCIENCES (pp. 356A–356A).

Presentations

Reynolds, L. ( 2017). Impact of Short-Term Reductions in Physical Activity on Cardio-Metabolic Health Oral Presentation The American College of Sports Medicine Annual Meeting .

Reynolds, L. ( 2016). Smoking During Pregnancy Increases Chemerin Expression in Neonatal Tissue Oral Presentation U.S. Developmental Origins of Health and Disease Inaugural Meeting Detroit, MI.

Reynolds, L., Joshua, D., Lindsay, P. G. and Pearson, K. J. (November , 2016). Maternal Exercise Alters Offspring Adipogenesis Poster Integrative Biology of Exercise .

Reynolds, L. ( 2015). Exercise as Medicine Oral Presentation Hadassah Jewish Women’s group for their Women’s Heart Healthy Month annual meeting Lexington, KY.

Reynolds, L. ( 2015). Insulin Resistance, Vascular Dysfunction, and the Impact of Daily Physical Activity Oral Presentation Human Performance Laboratory Ball State University, Muncie, IN.

Reynolds, L., Rashid, C. S., Platt, K. M., Jarrell, A. L., Swanson, H. I. and Pearson, K. J. (March , 2015). Maternal Polychlorinated Biphenyl 126 Exposure Alters Hepatic Gene Expression in Offspring Poster Society of Reproductive Investigation .

Boyle, L. J., Credeur, D. P., Holwerda, S. W., Leidy, H. J., Thyfault, J. P. and Fadel, P. J. (April , 2014). Acute reductions in daily physical activity negatively impacts glycemic control without changing insulin mediated blood flow Poster Association for Clinical and Translational Science .

Boyle, L. J., Credeur, D. P., Padilla, J., Fadel, P. J. and Thyfault, J. P. (April , 2014). Endothelial peNOS Signaling and ET-1 mRNA Expression During Acute Hyperinsulinemia in Type 2 Diabetes Poster Experimental Biology .

Boyle, L. J., Credeur, D. P., Jenkins, N. T., Padilla, J., Thyfault, J. P. and Fadel, P. J. (April , 2013). Five Days of Reduced Physical Activity Selectively Impairs Endothelial Function of the Inactive Limbs Poster Experimental Biology .

Reynolds, L. ( 2012). Altering Physical Activity: Impact on Endothelial Function and Insulin Stimulated Blood Flow Oral Presentation Department of Nutrition and Exercise Physiology University of Missouri, Columbia, MO.

Boyle, L. j., Credeur, D. P., Holwerda, S. W., Padilla, J., Leidy, H. L., Thyfault, J. P. and Fadel, P. J. (October , 2012). Alterations in endothelial function with Physical Inactivity: A Preliminary Report Poster Integrative Biology of Exercise .

Mikus, C. R., Libla, J. L., Fairfax, S., Boyle, L. J., Vianna, L., Oberlin, D. J., Uptergrove, G., Deo, S. H., Kim, A., Kanaley, J. A., Fadel, P. J. and Thyfault, J. P. ( 2010). Seven Days of Aerobic Exercise Augments Skeletal Muscle Blood Flow Responses to a Glucose Load in Patients with Type 2 Diabetes Poster The American Diabetes Association .

Boyle, L. J., Mikus, C., Libla, J., Oberlin, D. J., Fadel, P. and Thyfault, J. (October , 2010). Seven days of exercise training does not change GIP and GLP responses to a glucose challenge in obese subjects with type 2 diabetes Poster Integrative Physiology of Exercise .

Reynolds, L. ( 2009). Effects of Whole Body Vibration and Exercise on Fibrinolysis in Men Oral Presentation Central States Chapter of the American College of Sports Medicine annual meeting Columbia, MO.

Boyle, L. J. and Nagelkirk, P. R. ( 2009). Effects of Whole Body Vibration and Exercise on Fibrinolysis in Men Oral Presentation The Central States Chapter of the American College of Sports Medicine annual meeting .

Reynolds, L. ( 2008). The Influence of Hormone Suppression Therapy and Related Factors on Bone Mineral Density in Cancer Patients Oral Presentation Midwestern American College of Sports Medicine regional meeting. Bowling Green, Ohio.

Boyle, L. J., Hubbard, K., Hanna, L., Hargens, T. and Kaminsky, L. A. (October , 2008). The Influence of Hormone Suppression Therapy and Related Factors on Bone Mineral Density in Cancer Patients Oral Presentation The Midwestern American College of Sports Medicine regional meeting Bowling Green, Ohio.

Boyle, L. J., Rejc, J. M., Kaminsky, L. A., Strath, S. J. and Hargens, T. A. (May , 2008). Efficacy of increasing physical activity by 2000 steps/day in insufficiently active individuals Poster The American College of Sports Medicine annual meeting in Indianapolis, .

• 2018: Junior Faculty Research Mentoring Award, ��������